Dr. Debdutta Bhattacharya

Scientist Profile

Dr. Debdutta Bhattacharya

Scientist-E

Date of Joining : 07/05/2015
Date of Joining(present post): 01/09/2023
Address(O):

ICMR-Regional Medical Research Centre
Chandrasekharpur, Bhubaneswar-751 023
Odisha, India

Address(R):

Quarter No-C3, Staff Quarters
ICMR-Regional Medical Research Centre
Chandrasekharpur, Bhubaneswar-751 023
Odisha, India


Telephone no:

Fax no:

Mobile No:

Email Id:

drdebduttab.rmrc-od@gov.in

Social Account:

Educational Qualifications:

1) Graduation (B.Sc.) in Microbiology from Pune University in the year 2005
2) 2) Post graduation (M.Sc.) in Microbiology from Allahabad Agricultural Institute-Deemed University (Presently Sam Higginbottom University of Agriculture, Technology and Sciences) in the year 2007
3) PhD (Microbiology) from ICMR-Regional Medical Research Centre under Pondicherry University in the year 2013.


About Profile:

Research Interests:

Microbiology, Infectious Disease Epidemiology, One Health, Zoonotic Diseases, Antimicrobial   Resistance & Public Health

Professional experience:

Designation Institution Duration
Scientist-D ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India 1stSept., 2019-till date
Scientist-C ICMR- Regional Medical Research Centre, Bhubaneswar, Odisha, India 7th May, 2015-31st August, 2019
Scientist-B (Project) ICMR-National Institute of Traditional Medicine,
Belagavi, Karnataka
13th March, 2013-30th April, 2015
Scientist-B (Project) ICMR- Regional Medical Research Centre, Port Blair, A&N Islands, India 6th August, 2012-28th February, 2013

Projects being handled as PI:

Sl No. Name of the project Role (PI/Co-PI/Co-I) Funding agency Total duration
1 Laboratory surveillance system for antimicrobial resistance in community settings and understanding the perception and determinants leading to antimicrobial (mis)use in rural settings of Odisha & Chhattisgarh Principal Investigator ICMR 2021-24
2 Immune response to precautionary third dose of    COVISHIELD/COVAXIN among healthy adult population: an ICMR Cohort study, India Principal Investigator ICMR multicentric 2022-23
3 “One Health” strategy for elimination of human anthrax from an endemic district of Odisha: a demonstration project Co-Principal Investigator ICMR 2019-2022
4 Regional Hub for Health Technology Assessment Hub Coordinator DHR 2018-2025
5 Regional Virus Research and Diagnostic Laboratory Co-Investigator DHR 2019-2025
6 Demography Integrated Surveillance for Health Assessment (DISHA) on Dengue and Chikungunya in Tigiria block of Cuttack district, Odisha - A pilot study Co-Investigator DBT-BIRAC 2020-25
7 Odisha Tribal Health Survey Co-Investigator S&T Dept. Govt. of Odisha 2021-23

Publications in the last 5 years (Total publications:73)

#Equal contribution

Virology

  1. Parai D, Choudhary HR, Dash GC, Behera S, Mishra N, Pattnaik D, Raghav SK, Mishra SK, Sahoo SK, Swain A, Mohapatra I, Pattnaik M, Moharana A, Jena SR, Prahraj I, Subhadra S, Kanungo S, Bhattacharya D and Pati S. Dynamicity and persistence of severe acute respiratory syndrome coronavirus-2 antibody response after double dose and the third dose with BBV-152 and AZD1222 vaccines: A prospective, longitudinal cohort study. Front. Microbiol. 2022; 13:942659. doi: 10.3389/fmicb.2022.942659.
  2. Kshatri JS#, Giri S#, Bhattacharya D#, Palo SK, Praharaj I, Kanungo S, Turuk J, Ghosal J, Bhoi T, Pattnaik M, Singh H, Panda S, Pati S. Analysis of the COVID-19 testing parameters and progression of the pandemic at the district level: findings from the ICMR Hundred Million Test (HMT) database during the first wave in India. Int J Infect Dis. 2022;122:497-505.
  3. Mahapatra A#, Palo SK#, Bhattacharya D#, Kanungo S, Kshatri JS, Mishra BK, Mansingh A, Parai D, Pattnaik M, Choudhary HR, Dash GC, Mohanta AR, Bisoyee A, Mohanty P, Mandal N, Dayal R, Mitra A, Pati S. Trend in sero-prevalence of SARS-CoV-2 (IgG antibody) among tribal dominated population- Findings from Jharkhand, India. Indian J Med Res. 2022.
  4. Nair S, Joshi, A, Aggarwal S, Adhikari T; Mahajan N, Diwan V; Stephen A, Devi RK; Mishra BK; Yadav GK, Kohli R, Sahu D; Gulati BK, Sharma S; Yadav J, Ovung S, Duggal C; Sharma M, Bangar, SD; Andhalkar R, Rebecca PB; Rani S; Selvaraj P; Xavier G, Peter V, Watson B, Kannan T, Asmathulla KS, Bhattacharya D, Turuk J, Palo SK, Kanungo S, Behera AK, Pandey AK, Zaman K, Misra, Brij R, Kumar N, Behera SP, Singh R, Sarkar AH, NarainK, Rajnikant, Sahay S, Tiwari RR, Thomas BE, Panda S, Rao VV. Development & validation of scales to assess stigma related to COVID-19 in India. Indian J Med Res. 2022.
  5. Mishra SK, Pradhan SK, Pati S, Panda BK, Bhattacharya D, Sahu SK, Kshatri JS. Anti-SARS-CoV-2 antibodies among vaccinated healthcare workers: Repeated cross-sectional study. J Family Med Prim Care. 2022;11(5):1883-1889.
  6. Palo SK, Dubey S, Negi S, Sahay MR, Patel K, Swain S, Mishra BK, Bhuyan D, Kanungo S, Som M, Merta BR, Bhattacharya D, Kshatri JS, Pati S. Effective interventions to ensure MCH (Maternal and Child Health) services during pandemic related health emergencies (Zika, Ebola, and COVID-19): A systematic review. PLoS ONE. 2022; 17(5): e0268106. https://doi.org/10.1371/journal.pone.0268106
  7. Kar B, Dehury B, Singh MK, Pati S, Bhattacharya D. Identification of phytocompounds as newer antiviral drugs against COVID-19 through molecular docking and simulation based study. J Mol Graph Model. 2022;114:108192. doi: 10.1016/j.jmgm.2022.108192.
  8. Dash P, Mansingh A, Nayak SR, Sahoo D, Bhattacharya D, Kanungo S, Kshatri JS, Mishra BK, Pattnaik M, Parai D, Choudhury HR, Nayak S, Rana K, Alce A, Sahoo AK, Mohanty KC, Mohanty P, Doley C, Jain H, Majhi D, Patnaik P, Behuria S, Panda S, Bhoi S, Pati S, Palo SK. Infection, cases due to SARS-CoV-2 in rural areas during early COVID-19 vaccination: Findings from sero-survey study in a rural cohort of eastern India. Epidemiol Infect. 2022:1-27. doi: 10.1017/S0950268822000346.
  9. Mishra BK, Kanungo S, Patel K, Swain S, Dwivedy S, Panda S, Karna S, Bhuyan D, Som M, Merta BR, Bhattacharya D, Kshatri JS, Palo SK, Pati S. Resolution of Resilience: Empirical Findings on the Challenges Faced and the Mitigation Strategies Adopted by Community Health Workers (CHWs) to Provide Maternal and Child Health (MCH) Services during the COVID-19 Pandemic in the Context of Odisha, India. Healthcare (Basel). 2022;10(1):88. doi: 10.3390/healthcare10010088. PMID: 35052251.
  10. Choudhary HR, Parai D, Dash GC, Kshatri JS, Mishra N, Choudhary PK, Pattnaik D, Panigrahi K, Behera S, Sahoo NR, Podder S, Mishra A, Raghav SK, Mishra SK, Pradhan SK, Sahoo SK, Pattnaik M, Rout UK, Nanda RR, Mondal N, Kanungo S, Palo SK, Pati S, Bhattacharya D. Persistence of antibodies against Spike glycoprotein of SARS-CoV-2 in health care workers post double dose of BBV-152 and AZD1222 vaccines. Front Med (Lausanne). 2021;8:778129. 
  11. Dash GC, Subhadra S, Turuk J, Parai D, Rout UK, Rath S, Sabat J, Nanda RR, Choudhary HR, Pati S, Bhattacharya D. COVID-19 in children in Odisha state, India: a retrospective review. BMJ Paediatrics Open 2021 ;5: e001284.
  12. Parai D, Choudhary HR, Dash GC, Sahoo SK, Pattnaik M, Rout UK, Nanda RR, Kanungo S, Kshatri JS, Pati S, Bhattacharya D. Single-dose of BBV-152 and AZD1222 increases antibodies against Spike glycoprotein among healthcare workers recovered from SARS-CoV-2 infection. Travel Med Infect Dis. 2021; 44: 102170. doi: 10.1016/j.tmaid.2021.102170
  13. Dash GC, Subhadra S, Turuk J, Parai D, Rath S, Sabat J, Rout UK, Kanungo S, Choudhary HR, Nanda RR, Pattnaik M, Pati S, Bhattacharya D. Breakthrough SARS-CoV-2 infections among BBV-152 (COVAXIN®) and AZD1222 (COVISHIELDTM) recipients: Report from eastern state of India. J Med Virol. 2022; 94: 1201–1205.
  14. Dash GC, Parai D, Choudhary HR, Peter A, Rout UK, Nanda RR, Kshatri JS, Kanungo S, Palo SK, Mondal N, Pati S, Bhattacharya D. SARS-CoV-2 IgG antibody responses in rt-PCR positive cases: First report from India. Access Microbiology. 2021; 3(10):000267.
  15. Mishra BK, Bhattacharya D, Kshatri JS, Pati S. Natural Immunity against COVID-19 Significantly Reduces the Risk of Reinfection: Findings from a Cohort of Sero-Survey Participants. Viral Immunology 2021.
  16. Choudhary HR, Parai D, Dash GC, Peter A, Sahoo SK, Pattnaik M, Rout UK, Nanda RR, Pati S, Bhattacharya D. IgG antibody response against nucleocapsid and spike protein post-SARS-CoV-2 infection. Infection. 2021; 49(5):1045-1048.
  17. Murhekar MV, Bhatnagar T, Thangaraj JWV, Saravanakumar V, Kumar MS, Selvaraju S, Rade K, Girish Kumar CP, Sabarinathan R, Turuk A, Asthana S, Balachandar R, Bangar SD, Bansal AK, Chopra V, Das D, Deb AK, Devi KR, Dhikav V, Dwivedi GR, Muhammad Salim Khan S, Sunil Kumar M, Laxmaiah A, Madhukar M, Mahapatra A, Rangaraju C, Turuk J, Yadav R, Andhalkar R, Arunraj K, Bharadwaj DK, Bharti P, Bhattacharya D, Bhat J, Chahal AS, Chakraborty D, Chaudhury A, Deval H, Dhatrak S, Dayal R, Elantamilan D, Giridharan P, Haq I, Hudda RK, Jagjeevan B, Kalliath A, Kanungo S, Krishnan NN, Kshatri JS, Kumar A, Kumar N, Vinoth Kumar VG, Naga Lakshmi GGJ, Mehta G, Mishra NK, Mitra A, Nagbhushanam K, Nimmathota A, Nirmala AR, Pandey AK, Prasad GV, Qurieshi MA, Reddy SD, Robinson A, Sahay S, Saxena R, Sekar K, Shukla VK, Singh HB, Singh PK, Singh P, Singh R, Srinivasan N, Varma DS, Viramgami A, Wilson VC, Yadav S, Yadav S, Zaman K, Chakrabarti A, Das A, Dhaliwal RS, Dutta S, Kant R, Khan AM, Narain K, Narasimhaiah S, Padmapriyadarshini C, Pandey K, Pati S, Patil S, Rajkumar H, Ramarao T, Sharma YK, Singh S, Panda S, Reddy DCS, Bhargava B; ICMR serosurveillance group. SARS-CoV-2 sero-prevalence among general population and healthcare workers in India, December 2020 - January 2021. Int J Infect Dis. 2021; 108: 145-155.
  18. Dash GC, Rout UK, Nanda RR, Parai D, Choudhary HR, Kanungo S, Palo SK, Kshatri JS, Turuk J, Mishra B, Pati S, Bhattacharya D. Pooled testing for SARS-COV-2 infection in an automated high 2 throughput platform. J Clin Lab Anal. 2021; 35(7): e23835.
  19. Kshatri JS, Bhattacharya D, Kanungo S, Giri S, Palo SK, Parai D, Turuk J, Mansingh A, Choudhary H, Pattnaik M, Dash GC, Mohanty P, Mishra N, Satapathy DM, Sahoo S, Mx ICMR-RMRC [OdiSHA-COVID-19] Serosurvey team. Serological surveys to inform SARS-CoV-2 epidemic curve - a cross-sectional study from Odisha, India. Scientific Reports 2021; 11: 10551.
  20. Kshatri JS, Bhattacharya D, Praharaj I, Mansingh A, Parai D, Kanungo S, Palo SK, Giri S, Patnaik M, Barik SR, Dash GC, Choudhary H, Turuk J, Pati S. Seroprevalence of SARS-CoV-2 in Bhubaneswar, India: findings from 3 rounds of community surveys. Epidemiol Infect. 2021; 149: e139.
  21. Parai D, Dash GC, Choudhary HR, Peter A, Rout UK, Nanda RR, Kshatri JS, Kanungo S, Pati S, Bhattacharya D. Diagnostic accuracy comparison of three fully automated chemiluminescent immunoassay platforms for the detection of SARS-CoV-2 antibodies. J Virol Methods. 2021; 292: 114121. doi: 10.1016/j.jviromet.2021.114121
  22. Bhattacharya D, Parai D, Rout UK, Dash P, Nanda RR, Dash GC, Kanungo S, Palo SK, Giri S, Choudhary HR, Kshatri JS, Turuk J, Mishra BK, Lenka RK, Dash S, Pati S. Saliva for diagnosis of SARS-CoV-2: First report from India. J Med Virol. 2021; 93: 2529-2533.
  23. Dash P, Turuk J, Behera SK, Palo SK, Raghav SK, Ghosh A, Sabat J, Rath S, Subhadra S, Rana K, Bhattacharya D, Kanungo S, Kshatri JS, Mishra BK, Dash S, Parida A, Pati S. Sequence analysis of Indian SARS-CoV-2 isolates shows a stronger interaction of mutant receptor-binding domain with ACE2. Int J Infect Dis. 2021; 104: 491-500.
  24. Raghav S, Ghosh A, Turuk J, Kumar S, Jha A, Madhulika S, Priyadarshini M, Biswas VK, Shyamli PS, Singh B, Singh N, Singh D, Datey A, Avula K, Smita S, Sabat J, Bhattacharya D, Kshatri JS, Vasudevan D, Suryawanshi A, Dash R, Senapati S, Beuria TK, Swain R, Chattopadhyay S, Syed GH, Dixit A, Prasad P, Odisha COVID-19 Study Group, ILS COVID-19 Team, Pati S, Parida A. Analysis of Indian SARS-CoV-2 Genomes Reveals Prevalence of D614G Mutation in Spike Protein Predicting an Increase in Interaction With TMPRSS2 and Virus Infectivity. Microbiol2020; 11: 594928.
  25. Kshatri JS, Turuk J, Sabat J, Subhadra S, Ho LM, Rath S, Palo SK, Bhattacharya D, Dwibedi B, Pati S. Epidemiology of viral disease outbreaks in Odisha, India (2010-2019). Epidemiol Infect 2020; 148: e162.

    Diarrhoeal Diseases, Zoonotic Diseases & Antibiotic Resistance

  26. Parai D, Pattnaik M, Kshatri JS, Rout UK, Peter A, Nanda RR, Sahoo SK, Mansingh A, Choudhary HR, Dash GC, Praharaj I, Bhattacharya D, Pati S. Scrub typhus seroprevalence from an eastern state of India: Findings from the state-wide serosurvey. Trans Royal Society Trop Med Hyg. 2022.
  27. Pattnaik M, Kshatri JS, Choudhary HR, Parai D, Shandilya J, Mansingh A, Padhi AK, Pati S, Bhattacharya D. Assessment of socio-behavioural correlates and risk perceptions regarding anthrax disease in tribal communities of Odisha, Eastern India. BMC Infectious Diseases. 2022; 22:53.
  28. Kar B, Chandar B, Rachana SS, Bhattacharya H, Bhattacharya D. Antibacterial & genotoxic activity of Bixa orellana, a folk medicine and food supplement against multidrug resistant clinical isolates. J Herbal Med 2022; 32. doi: 10.1016/j.hermed.2021.100502.
  29. Kar B, Kundu CN, Pati S, Bhattacharya D. Discovery of phyto-compounds as novel inhibitors against NDM-1 and VIM-1 protein through virtual screening and molecular modelling. J Biomol Struct Dyn. 2021:1-14. doi: 10.1080/07391102.2021.2019125. Epub ahead of print. PMID: 34961397.
  30. Bhattacharya D, Kshatri JS, Choudhary HR, Parai D, Shandilya J, Mansingh A, Pattnaik M, Mishra K, Padhi SP, Padhi A, Pati S. One Health approach for elimination of human anthrax in a tribal district of Odisha: Study protocol. PLOS One 2021; 16. e0251041.
  31. Sahoo KC, Negi S, Dash GC, Sahoo RK, Kshatri JS, Panda S, Pattanaik M, Badaik G, Pati S, Bhattacharya D. Health system preparedness and community participation in Japanese encephalitis/acute Encephalitis encephalitis Syndrome syndrome (JE/AES) prevention in a tribal district of Odisha, India. Indian J Med Res.2021; 153: 388-393.
  32. Mansingh A#, Choudhary HR#, Shandilya J#, Bhattacharya D#,Kshatri JS#, Parai D, Pattanaik M, Padhi AK, Jain HK, Mohanty P, Kanungo S, Pati S. A qualitative exploratory study using One Health Approach for developing an intervention package for elimination of human Anthrax in an endemic district of Odisha. Indian J Med Res. 2021;153: 394-400.
  33. Kar B, Sharma M, Peter A, Chetia P, Neog B, Borah A, Pati S, Bhattacharya D. Prevalence and molecular characterization of β-lactamase producers and fluoroquinolone resistant clinical isolates from North East India. J Infec Pub Health 2021; 14(5): 628-637
  34. Chaaithanya IK#, Bhattacharya D#, Patil T, Ghargi KV, Kalal S, Roy S. Etiology of Non-Rotaviral Diarrhea in Hospitalized Children under Five Years of Age in South-Western India.Indian J Pediatr. 2020 ;87(7):571-572.
  35. Sahoo KC, Negi S, Barla D, Badaik G, Sahoo S, Bal M, Padhy AK, Pati S, Bhattacharya D. Thelandscape of Anthrax prevention and control: stakeholders’perceptive in Odisha, India. Int J Environ Res Public Health 2020; 17(9): 3094.
  36. Moharana SS, Panda RK, Dash M, Chayani N, Bokade P, Pati S, Bhattacharya D. Etiology of childhood diarrhoea among under five children and molecular analysis of antibiotic resistance in isolated enteric bacterial pathogens from a tertiary care hospital, Eastern Odisha, India. BMC Infect Dis 2019; 19: 1018. doi:10.1186/s12879-019-4501-6
  37. Chandar B, Bhattacharya D. Role of natural product in modulation of drug transporters and New Delhi Metallo- β lactamases. Current Topics in Medicinal Chemistry 2019: 19(10): 874 – 885. doi: 10.2174/1871529X19666190415110724.
  38. Chandar B, Pati S, Bhattacharya D. An overview of New Delhi Metallo-βeta lactamase-1 and Extended Spectrum Beta Lactamase producing bacteria: need for an alternate. J Antimicrob Agents 2018, 4(1):155.  DOI: 10.4172/2472-1212.1000155

    Tribal Health & Other

  39. Sahoo KC, Dash GC, Panda S, Kshatri JS, Uddin A, Pattnaik M, Sahoo RK, Diwedi R, Palo SK, Bhattacharya D, Pati S. Impact of smokeless cooking fuel use on health status of women in a rural setting of eastern India.Int J Environmental Health Res 2022;
  40. Athe R, Dwivedi R, Sahoo KC, Bhattacharya D, Jain S, Pati S. A systematic review and meta-analysis of screening and diagnostic accuracy for hearing loss among under-five children in South-Asian region. Int J Human Rights Healthcare. 2021
  41. Dwivedi R, Athe R, Pati S, Sahoo KC, Bhattacharya D. Mapping of Health Technology Assessment (HTA) teaching and training initiatives: Landscape for evidence-based policy decisions in India. J Family Med Prim Care 2020; 9: 5458-67.
  42. Sahoo KC, Dwivedi R, Athe R, Bhattacharya D, Rajsekhar K, Pati S. Stakeholders’ Perspective for Improved Universal Newborn Hearing Screening Uptake in Odisha, India. J Trop Pediatr 2020; fmaa062. https://doi.org/10.1093/tropej/fmaa062

NCBI GenBank submissions

Accession Numbers

HM068906-HM068910, HQ166944-HQ166949, HQ123622-HQ123624, HQ203196- HQ203209, JQ070959-JQ070963, JN972433-JN972437, HQ246165-HQ246194, JQ973859-JQ973861, JQ692605-JQ692609 and JX112038-JX112042, MT796264 and MT796265 (RdRp gene of SARS-CoV-2), MT798848 and MT798849 (S gene of SARS-CoV-2), MW566169-MW566172 (CTX-M3 & CTX-M).

Awards & Achievements:

  1. 3rd prize for his oral presentation at Health Research Conclave organized as part of IndiaInternational Science Festival, 2020.
  2. ICMR Centenary Gold Medal for outstanding research contributions in the field of Shigellosis in Andaman & Nicobar Islands, India, Nov 2011.

Recognitions:

  1. Member, State Zoonotic Coordination Committee, Dept. of Health & Family Welfare, Govt. of Odisha, Bhubaneswar.
  2. Member, State Rapid Response Team for outbreak investigation, Dept. of Health &Family Welfare, Govt. of Odisha, Bhubaneswar.
  3. Member, Technical Evaluation & Managerial Committee, Odisha State Medical Corporation Ltd, (OSMCL) Govt. of Odisha.
  4. Member of the committee for preparation of SOP for Laboratory Surveillance of Acute Encephalitis Syndrome (AES) Cases: Guideline for Sample Collection, Transport and Laboratory Testing for on National Vector Borne Diseases Control Programme (NVBDCP), of Health &Family Welfare, Govt. of Odisha, Bhubaneswar.
  5. PhD examiner for Pondicherry University & SRM University

Editorial board member&Reviewer

  1. Editorial board member for the journals likePLOS One, Frontiers in Medicine, Frontiers in Public Health, Frontiers in Antibiotics, EC Microbiology.
  2. Reviewer for Journal of Antimicrobial Chemotherapy; BMJ Open, Journal of Infection in Developing Countries; Journal of Health, Population and Nutrition; Journal of Biomedical Research; Journal of Clinical Epidemiology; BMC Research Notes; BMC Infectious Diseases; African Journal of Microbiology Research; Journal of Alternative and Complementary Medicine; Microbial Pathogenesis.

PhD/PDF students:

  1. Bipasa Kar, CSIR-JRF registered for PhD under KIIT University, Bhubaneswar (2018-22)
  2. Usha Kiran Rout, registered for PhD under KIIT University, Bhubaneswar (2020 onwards)
  3. Hariram Choudhary, registered for PhD under SRM Institute of Science and Technology (SRMIST), Chennai (2022 onwards)
  4. BrindaChandar, ICMR-PDF, during 2018-19.

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